Evaluation of a New Polysulfone Hemofilter for Continuous Renal Replacement Therapy
- 7 June 2011
- journal article
- clinical trial
- Published by S. Karger AG in Blood Purification
- Vol. 32 (2), 133-138
- https://doi.org/10.1159/000325221
Abstract
New strategies using continuous renal replacement therapy as a tool to achieve immunomodulation in septic acute kidney injury have been proposed. The hypothesis is based on the possibility to remove inflammatory mediators and oxidants in a wide spectrum of molecular weights, thanks to new, highly permeable synthetic membranes. A new polysulfone hemofilter with high permeability and a sharp high cut-off membrane (CUREFLO™; Asahi Kasei Kuraray Medical Co., Ltd., Tokyo, Japan) has been evaluated in this study to assess IL-6 and advanced oxidation protein product removal in critically ill patients undergoing continuous renal replacement therapy. Unit performance, sieving coefficients and clearances were evaluated in fourteen patients undergoing continuous veno-venous hemofiltration and continuous veno-venous hemodialysis.This publication has 17 references indexed in Scilit:
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