A Randomized Controlled Trial of Acetyl Salicyclic Acid in the Secondary Prevention of Mortality from Myocardial Infarction
- 9 March 1974
- Vol. 1 (5905), 436-440
- https://doi.org/10.1136/bmj.1.5905.436
Abstract
The results of a randomized controlled trial of a single daily dose of acetyl salicylic acid (aspirin) in the prevention of reinfarction in 1,239 men who had had a recent myocardial infarct were statistically inconclusive. Nevertheless, they showed a reduction in total mortality of 12% at six months and 25% at twelve months after admission to the trial. Further trials are urgently required to establish whether or not this effect is real.Keywords
This publication has 6 references indexed in Scilit:
- EFFECTS OF SALICYLATES ON HUMAN PLATELETSThe Lancet, 1968
- Salicylates, platelets and adenine nucleotidesNaunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1968
- IMPAIRED PLATELET/CONNECTIVE-TISSUE REACTION IN MAN AFTER ASPIRIN INGESTIONThe Lancet, 1967
- The quantitation of platelet aggregation induced by four compounds: a study in relation to myocardial infarction.1966
- Aggregation of Blood Platelets by Adenosine Diphosphate and its ReversalNature, 1962
- Maximum utilization of the life table method in analyzing survivalJournal of Chronic Diseases, 1958