Regulation of WASP/WAVE proteins
Open Access
- 27 September 2004
- journal article
- review article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 166 (7), 957-962
- https://doi.org/10.1083/jcb.200403127
Abstract
Despite their homology, the regulation of WASP and WAVE, activators of Arp2/3-dependent actin polymerization, has always been thought to be different. Several recent studies have revealed new aspects of their regulation, highlighting its complexity and the crucial role of post-translational modifications. New data also suggest additional functions for WASP family proteins, pushing us to reconsider existing models.Keywords
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