The Virtual Physiological Human T ool K it
- 28 August 2010
- journal article
- Published by The Royal Society in Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
- Vol. 368 (1925), 3925-3936
- https://doi.org/10.1098/rsta.2010.0144
Abstract
The Virtual Physiological Human (VPH) is a major European e-Science initiative intended to support the development of patient-specific computer models and their application in personalized and predictive healthcare. The VPH Network of Excellence (VPH-NoE) project is tasked with facilitating interaction between the various VPH projects and addressing issues of common concern. A key deliverable is the ‘VPH T ool K it ’—a collection of tools, methodologies and services to support and enable VPH research, integrating and extending existing work across Europe towards greater interoperability and sustainability. Owing to the diverse nature of the field, a single monolithic ‘toolkit’ is incapable of addressing the needs of the VPH. Rather, the VPH T ool K it should be considered more as a ‘toolbox’ of relevant technologies, interacting around a common set of standards. The latter apply to the information used by tools, including any data and the VPH models themselves, and also to the naming and categorizing of entities and concepts involved. Furthermore, the technologies and methodologies available need to be widely disseminated, and relevant tools and services easily found by researchers. The VPH-NoE has thus created an online resource for the VPH community to meet this need. It consists of a database of tools, methods and services for VPH research, with a Web front-end. This has facilities for searching the database, for adding or updating entries, and for providing user feedback on entries. Anyone is welcome to contribute.Keywords
This publication has 16 references indexed in Scilit:
- High-Throughput All-Atom Molecular Dynamics Simulations Using Distributed ComputingJournal of Chemical Information and Modeling, 2010
- FieldML: concepts and implementationPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2009
- ACEMD: Accelerating Biomolecular Dynamics in the Microsecond Time ScaleJournal of Chemical Theory and Computation, 2009
- Science wikinomicsEMBO Reports, 2009
- The impact of accelerator processors for high-throughput molecular modeling and simulationDrug Discovery Today, 2008
- The EuroPhysiome, STEP and a roadmap for the virtual physiological humanPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2008
- Anatomy Ontologies for BioinformaticsPublished by Springer Science and Business Media LLC ,2008
- Systems biology standards—the community speaksNature Biotechnology, 2007
- Enabling Data Sharing and Collaboration in Complex Systems ApplicationsPublished by Springer Science and Business Media LLC ,2007
- CellML: its future, present and pastProgress in Biophysics and Molecular Biology, 2004