Ancient genomes link early farmers from Atapuerca in Spain to modern-day Basques
Open Access
- 8 September 2015
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences of the United States of America
- Vol. 112 (38), 11917-11922
- https://doi.org/10.1073/pnas.1509851112
Abstract
The consequences of the Neolithic transition in Europe—one of the most important cultural changes in human prehistory—is a subject of great interest. However, its effect on prehistoric and modern-day people in Iberia, the westernmost frontier of the European continent, remains unresolved. We present, to our knowledge, the first genome-wide sequence data from eight human remains, dated to between 5,500 and 3,500 years before present, excavated in the El Portalón cave at Sierra de Atapuerca, Spain. We show that these individuals emerged from the same ancestral gene pool as early farmers in other parts of Europe, suggesting that migration was the dominant mode of transferring farming practices throughout western Eurasia. In contrast to central and northern early European farmers, the Chalcolithic El Portalón individuals additionally mixed with local southwestern hunter–gatherers. The proportion of hunter–gatherer-related admixture into early farmers also increased over the course of two millennia. The Chalcolithic El Portalón individuals showed greatest genetic affinity to modern-day Basques, who have long been considered linguistic and genetic isolates linked to the Mesolithic whereas all other European early farmers show greater genetic similarity to modern-day Sardinians. These genetic links suggest that Basques and their language may be linked with the spread of agriculture during the Neolithic. Furthermore, all modern-day Iberian groups except the Basques display distinct admixture with Caucasus/Central Asian and North African groups, possibly related to historical migration events. The El Portalón genomes uncover important pieces of the demographic history of Iberia and Europe and reveal how prehistoric groups relate to modern-day people.Keywords
This publication has 48 references indexed in Scilit:
- DNA analysis of an early modern human from Tianyuan Cave, ChinaProceedings of the National Academy of Sciences of the United States of America, 2013
- An integrated map of genetic variation from 1,092 human genomesNature, 2012
- The Basque Paradigm: Genetic Evidence of a Maternal Continuity in the Franco-Cantabrian Region since Pre-Neolithic TimesAmerican Journal of Human Genetics, 2012
- Analysis of High-Throughput Ancient DNA Sequencing DataPublished by Springer Science and Business Media LLC ,2011
- Illumina Sequencing Library Preparation for Highly Multiplexed Target Capture and SequencingCold Spring Harbor Protocols, 2010
- Reconstructing Indian population historyNature, 2009
- The Sequence Alignment/Map format and SAMtoolsBioinformatics, 2009
- Fast and accurate short read alignment with Burrows–Wheeler transformBioinformatics, 2009
- A Complete Neandertal Mitochondrial Genome Sequence Determined by High-Throughput SequencingCell, 2008
- Language-tree divergence times support the Anatolian theory of Indo-European originNature, 2003