Experimental retinal branch vein occlusion in rhesus monkeys. I. Clinical appearances.
Open Access
- 1 June 1979
- journal article
- research article
- Published by BMJ in British Journal of Ophthalmology
- Vol. 63 (6), 377-387
- https://doi.org/10.1136/bjo.63.6.377
Abstract
Branch and hemisphere vein occlusion were produced in rhesus monkeys by argon laser photocoagulation. The following observations were made: (1) Immediately after occlusion there was venous dilatation, delayed filling of the artery, delayed drainage by the occluded vein, and capillary leakage. (2) Two patterns of evolution were identified within the first week. In some animals the fundus changes resolved and the retina returned to normal, while in others there was progressive retinal capillary closure. (3) Those animals destined to have capillary closure had diffuse or cluster retinal haemorrhages at 24 hours. (4) Capillary closure took place over 1 week and was usually complete over large areas of retina. (5) Retinal atrophy and major vessel changes occurred over several weeks. (6) Retinal revascularisation occurred in those areas of closure, though this was often limited. It was concluded that the early changes mimicked those seen in human retinal vein occlusion, though persistent retinal oedema and preretinal neovascularisation were not identified.Keywords
This publication has 14 references indexed in Scilit:
- BRANCH VEIN OCCLUSION BY PHOTOCOAGULATION IN THE RABBIT EYEActa Ophthalmologica, 2009
- Experimental retinal branch vein occlusion in rhesus monkeys. III. Histopathological and electron microscopical studies.British Journal of Ophthalmology, 1979
- Experimental retinal branch vein occlusion in rhesus monkeys. II. Retinal blood flow studies.British Journal of Ophthalmology, 1979
- New vessel formation in retinal branch vein occlusion.British Journal of Ophthalmology, 1976
- Experimental Retinal Branch Vein OcclusionAmerican Journal of Ophthalmology, 1970
- A Fluorescein Angiographic Study of Macular Dysfunction Secondary to Retinal Vascular DiseaseAmerican Journal of Ophthalmology, 1968
- Occlusion of the central retinal vessels.British Journal of Ophthalmology, 1965
- Histopathology of Experimental Photocoagulation in the Dog EyeAmerican Journal of Ophthalmology, 1963
- Retinal Vein OcclusionAmerican Journal of Ophthalmology, 1961
- Retinal Vein Occlusion:*American Journal of Ophthalmology, 1951