LACTATION BIOLOGY SYMPOSIUM: The effect of nutrient intake from milk or milk replacer of preweaned dairy calves on lactation milk yield as adults: A meta-analysis of current data1
- 1 February 2013
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Animal Science
- Vol. 91 (2), 706-712
- https://doi.org/10.2527/jas.2012-5834
Abstract
Data from calf studies conducted over the past 20 yr has shown that preweaning nutrient intake, from milk or milk replacer, can have profound effects on development of the calf that enhance first lactation and lifetime productivity. Many of the studies show positive but not significant effects of preweaning nutrition on long-term productivity, primarily due to a lack of power, usually due to inadequate animal numbers per treatment. Meta-analyses were conducted using Comprehensive Meta-Analysis (CMA) software (version 2.2.064; Biostat, Englewood, NJ; Borenstein et al., 2005) to evaluate the effects of preweaning nutrient intake and preweaning ADG on first lactation milk production from studies where milk yield and preweaning treatment data were adequately described. Currently, 12 studies have been reported, describing milk yield of calves that had been fed various levels of preweaning nutrients, from both milk and milk replacer, and 11 evaluated the effect of preweaning ADG on long-term productivity. The estimated effect size for treatment (level of milk or milk replacer intake) and ADG were calculated. Using a random effects model, the overall milk yield response based on treatment was 435 ± 117 kg/lactation (P < 0.001), demonstrating that among the data sets milk yield in the first lactation was increased by increasing nutrient intake from milk or milk replacer in preweaned calves. Meta-regression of the effect of ADG resulted in the following equation: milk yield = –106 kg + 1,551.4 kg × ADG (kg/d; P = 0.01) indicating that for every kilogram of preweaning ADG, first lactation milk yield increased by 1,550 kg. Furthermore, the meta-analysis yielded an odds ratio of 2.09 (P = 0.001) indicating that calves fed for greater preweaning ADG were 2 times more likely to have greater milk yield in the first lactation. Finally, the 2001 Dairy NRC calf model was used to estimate the difference, within study, of intake over maintenance from milk replacer, using either the actual data or the published ADG; the difference in intake over maintenance was used as a predictor in a meta-regression and resulted in the following equation: milk yield = –60 kg + 1,100 kg × estimated difference in intake over maintenance (P = 0.02). The data demonstrate that nutrient intake from milk or milk replacer during the preweaning period positively impacted long-term productivity of dairy calves and provides new management opportunities to improve milk yield of dairy cattle. These data appear to indicate that there are significant developmental functions being programmed in the neonatal calf that require further investigation. Copyright © 2013. American Society of Animal Science .Keywords
This publication has 25 references indexed in Scilit:
- Effect of intensified feeding of heifer calves on growth, pubertal age, calving age, milk yield, and economicsJournal of Dairy Science, 2011
- Epigenetic Programming of Porcine Endometrial Function and the Lactocrine HypothesisReproduction in Domestic Animals, 2008
- Early life programming of obesity and metabolic diseasePhysiology & Behavior, 2008
- A Meta-Analysis of the Impact of Monensin in Lactating Dairy Cattle. Part 1. Metabolic EffectsJournal of Dairy Science, 2008
- Growth and body composition of dairy calves fed milk replacers containing different amounts of protein at two feeding rates1Journal of Animal Science, 2006
- Effects of Relaxin on Neonatal Porcine Uterine Growth and DevelopmentAnnals of the New York Academy of Sciences, 2005
- Composition of Growth of Holstein Calves Fed Milk Replacer from Birth to 105-Kilogram Body WeightJournal of Dairy Science, 2001
- Increased Weight Gain and Effects on Production Parameters of Holstein Heifer Calves That Were Allowed to Suckle from Birth to Six Weeks of AgeJournal of Dairy Science, 1997
- Bias in meta-analysis detected by a simple, graphical testBMJ, 1997
- Effects of Passive Immunity on Subsequent Production in Dairy HeifersJournal of Dairy Science, 1989