Prenylated Proteins: the Structure of the Isoprenoid Group
- 19 January 1990
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 247 (4940), 318-320
- https://doi.org/10.1126/science.2296720
Abstract
The mevalonate-derived portion of a prenylated protein from Chinese hamster ovary cells has been established as diterpenoid (C20). This group is linked to a carboxyl-terminal cysteine as a thioether. It was removed from the protein by hydrazinolysis followed by Raney nickel desulfurization, and the resulting hydrocarbon fraction was analyzed by gas chromatography-mass spectrometry.Keywords
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