The application of CAR-T cell therapy in hematological malignancies: advantages and challenges
Open Access
- 5 April 2018
- journal article
- review article
- Published by Elsevier BV in Acta Pharmaceutica Sinica. B
- Vol. 8 (4), 539-551
- https://doi.org/10.1016/j.apsb.2018.03.001
Abstract
No abstract availableKeywords
Funding Information
- National Natural Science Foundation of China (31670880, 31370868)
- Guangdong Natural Science Fund for Distinguished Young Scholars (2016A030306004)
- Guangzhou Pearl River New Star Program (201610010064)
- Guangdong Innovative Research Team Program (Guangdong Special Support Program for Youth Science and Technology Innovation Talents, 2015TQ01R473, 2011Y035)
This publication has 148 references indexed in Scilit:
- Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid LeukemiaNew England Journal of Medicine, 2013
- TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer ImmunotherapyMolecular Therapy Nucleic Acids, 2013
- Inducible Apoptosis as a Safety Switch for Adoptive Cell TherapyNew England Journal of Medicine, 2011
- Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid LeukemiaNew England Journal of Medicine, 2011
- T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced LeukemiaScience Translational Medicine, 2011
- CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemiaLeukemia, 2011
- NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Epidemiology and Natural History of Relapse following Allogeneic Cell TransplantationTransplantation and Cellular Therapy, 2010
- Infection and Killing of Multiple Myeloma by AdenovirusesHuman Gene Therapy, 2010
- Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In VivoMolecular Therapy, 2009
- Graft-versus-host disease after donor leukocyte infusions: presentation and managementBest Practice & Research Clinical Haematology, 2008