A FOXO1-induced oncogenic network defines the AML1-ETO preleukemic program
Open Access
- 7 September 2017
- journal article
- Published by American Society of Hematology in Blood
- Vol. 130 (10), 1213-1222
- https://doi.org/10.1182/blood-2016-11-750976
Abstract
Key Points Increased FOXO1 is oncogenic in human CD34+ cells and promotes preleukemia transition. FOXO1 is required by AE preleukemia cells for the activation of a stem cell molecular program.Keywords
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