Prenatal diagnosis of non‐immune hydrops fetalis: what do we tell the parents?
Open Access
- 4 January 2011
- journal article
- review article
- Published by Wiley in Prenatal Diagnosis
- Vol. 31 (2), 186-195
- https://doi.org/10.1002/pd.2677
Abstract
Objective The aim of this study is to outline the aetiology and outcome of a series of fetuses with non‐immune hydrops (NIH), detected prenatally. The findings are compared with a comprehensive review of recent reports. Methods This is a retrospective study reviewing all pregnancies complicated by NIH in the fetus and continued after 20 weeks of pregnancy over a period of 10 years. Outcome was obtained from postmortem reports, discharge summaries, communication with the clinicians or information from the parents. A literature search was also performed to identify all reports on NIH in the last 10 years. Results Seventy‐one fetuses affected by NIH were included in this study. The aetiology of the NIH was identified prenatally in 40 cases. The most common causes of NIH were thoracic disorders, infections and cardiovascular disorders. Forty‐four of the 71 (62%) fetuses were live‐born. There were 10 neonatal deaths. Of the remaining 34 babies, 17 infants survived without morbidity. Conclusion The survival rate of NIH is at least 48% in this study. Prenatal identification of the cause is possible in 56% of cases. The risk of neurodevelopmental delay in those that survive is 3 of 28 (11%). Copyright © 2011 John Wiley & Sons, Ltd.Keywords
This publication has 19 references indexed in Scilit:
- Hydrops Fetalis: A Retrospective Review of Cases Reported to a Large National Database and Identification of Risk Factors Associated With DeathPublished by American Academy of Pediatrics (AAP) ,2007
- Nonimmune Hydrops Fetalis Diagnosed during the Second Half of Pregnancy in Southern ChinaFetal Diagnosis and Therapy, 2007
- Prognostic Factors and Clinical Features in Liveborn Neonates with Hydrops FetalisAmerican Journal of Perinatology, 2006
- Severity of Non-Immune Hydrops Fetalis at Birth Continues to Predict Survival despite Advances in Perinatal CareFetal Diagnosis and Therapy, 2006
- A cardiovascular profile score in the surveillance of fetal hydropsThe Journal of Maternal-Fetal & Neonatal Medicine, 2006
- Etiology and Outcome of Non-Immune Hydrops fetalis in Southern ThailandGynecologic and Obstetric Investigation, 2005
- Analysis of outcome in hydrops fetalis in relation to gestational age at diagnosis, cause and treatmentActa Obstetricia et Gynecologica Scandinavica, 2001
- Etiology and outcome of hydrops fetalisThe Journal of Maternal-Fetal & Neonatal Medicine, 2001
- Etiology and outcome of second trimester non‐immunologic fetal hydropsActa Obstetricia et Gynecologica Scandinavica, 2000
- Revision of a Parent-Completed Developmental Screening Tool: Ages and Stages QuestionnairesJournal of Pediatric Psychology, 1997