Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury
- 25 December 2011
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature Medicine
- Vol. 18 (1), 166-171
- https://doi.org/10.1038/nm.2600
Abstract
Ali Erturk and colleagues present a novel tetrahydrofuran-based histological tissue clearing procedure that renders fixed and unsectioned adult CNS tissue (spinal cord and brainstem) transparent and, as such, fully amenable to a range of different optical imaging techniques. This three-dimensional imaging method can be used for studying axon regeneration and glial reactions.Keywords
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