Early Events in Antigen‐Specific Regulatory T Cell Induction via Nasal and Oral Mucosa
- 1 December 2004
- journal article
- Published by Wiley in Annals of the New York Academy of Sciences
- Vol. 1029 (1), 385-389
- https://doi.org/10.1196/annals.1309.045
Abstract
Mucosal Tr prevent harmful immune responses to innocuous antigens that are encountered at the mucosae. This unique subset of Tr is adaptive, antigen specific, and suppresses irrespective of cytokine polarization. Here we study the earliest events of mucosal Tr induction and factors that control their differentiation from naive T cells.Keywords
This publication has 13 references indexed in Scilit:
- Early Events in Peripheral Regulatory T Cell Induction via the Nasal MucosaPublished by The American Association of Immunologists ,2003
- Functional CD25– and CD25+ mucosal regulatory T cells are induced in gut‐draining lymphoid tissue within 48 h after oral antigen applicationEuropean Journal of Immunology, 2003
- Antigen presentation to naive CD4 T cells in the lymph nodeNature Immunology, 2003
- Nasal tolerance induces antigen-specific CD4+CD25- regulatory T cells that can transfer their regulatory capacity to naive CD4+ T cells.International Immunology, 2003
- Orally Tolerized T Cells Are Only Able to Enter B Cell Follicles Following Challenge with Antigen in Adjuvant, but They Remain Unable to Provide B Cell HelpPublished by The American Association of Immunologists ,2002
- Induction and mechanism of action of transforming growth factor‐β‐secreting Th3 regulatory cellsImmunological Reviews, 2001
- Type 1 T regulatory cellsImmunological Reviews, 2001
- T‐cell regulation of peripheral tolerance and immunity: the potential role for Notch signallingImmunology, 2000
- Modulating Dendritic Cells to Optimize Mucosal Immunization ProtocolsThe Journal of Immunology, 1999
- Intranasally Induced Immunological Tolerance Is Determined by Characteristics of the Draining Lymph Nodes: Studies with OVA and Human Cartilage gp-39The Journal of Immunology, 1999