Compliance with and effectiveness of adaptive servoventilation versus continuous positive airway pressure in the treatment of Cheyne-Stokes respiration in heart failure over a six month period
- 10 October 2005
- Vol. 92 (3), 337-342
- https://doi.org/10.1136/hrt.2005.060038
Abstract
Objective: To compare compliance with and effectiveness of adaptive servoventilation (ASV) versus continuous positive airway pressure (CPAP) in patients with the central sleep apnoea syndrome (CSA) with Cheyne-Stokes respiration (CSR) and with congestive heart failure in terms of the apnoea–hypopnoea index (AHI), quality of life, and left ventricular ejection fraction (LVEF) over six months. Methods: 25 patients (age 28–80 years, New York Heart Association (NYHA) class II–IV) with stable congestive heart failure and CSA-CSR were randomly assigned to either CPAP or ASV. At inclusion, both groups were comparable for NYHA class, LVEF, medical treatment, body mass index, and CSA-CSR. Results: Both ASV and CPAP decreased the AHI but, noticeably, only ASV completely corrected CSA-CSR, with AHI below 10/h. At three months, compliance was comparable between ASV and CPAP; however, at six months compliance with CPAP was significantly less than with ASV. At six months, the improvement in quality of life was higher with ASV and only ASV induced a significant increase in LVEF. Conclusion: These results suggest that patients with CSA-CSR may receive greater benefit from treatment with ASV than with CPAP.Keywords
This publication has 34 references indexed in Scilit:
- Neurohormones in heart failure: predicting outcomes, optimizing careEuropean Heart Journal, 2004
- Sleep Apnea and Heart FailureCirculation, 2003
- Cardiovascular Effects of Continuous Positive Airway Pressure in Patients with Heart Failure and Obstructive Sleep ApneaNew England Journal of Medicine, 2003
- Hemodynamic Effects of Bilevel Nasal Positive Airway Pressure Ventilation in Patients with Heart FailureRespiration, 1999
- Improvement of exercise capacity with treatment of Cheyne-Stokes respiration in patients with congestive heart failureJournal of the American College of Cardiology, 1996
- Daytime Sleepiness in Patients With Congestive Heart Failure and Cheyne-Stokes RespirationSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 1995
- Effect of Continuous Positive Airway Pressure on Intrathoracic and Left Ventricular Transmural Pressures in Patients With Congestive Heart FailureCirculation, 1995
- Continuous versus bilevel positive airway pressure for obstructive sleep apnea.American Journal of Respiratory and Critical Care Medicine, 1995
- Effect of Nasal Continuous Positive Airway Pressure on Cardiac Output and Oxygen Delivery in Patients with Congestive Heart FailureSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 1992
- Obstructive Sleep Apnea Treated by Independently Adjusted Inspiratory and Expiratory Positive Airway Pressures via Nasal MaskSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 1990