Biologic and Clinical Perspectives on Thyroid Cancer
Top Cited Papers
- 15 September 2016
- journal article
- review article
- Published by Massachusetts Medical Society in The New England Journal of Medicine
- Vol. 375 (11), 1054-1067
- https://doi.org/10.1056/nejmra1501993
Abstract
As in many cancers, genetic analysis of thyroid cancers has identified subgroups that differ in their pathogenesis and has defined targets that make the cancer susceptible to particular therapies. Recent progress leading to new treatments is reviewed.This publication has 88 references indexed in Scilit:
- Vemurafenib in patients with BRAFV600E-positive metastatic or unresectable papillary thyroid cancer refractory to radioactive iodine: a non-randomised, multicentre, open-label, phase 2 trialThe Lancet Oncology, 2016
- Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal CancerJournal of Clinical Oncology, 2015
- Integrated Genomic Characterization of Papillary Thyroid CarcinomaCell, 2014
- Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiationDevelopmental Biology, 2013
- Clinical outcomes and molecular profile of differentiated thyroid cancers with radioiodine-avid distant metastases.Journal of Clinical Endocrinology & Metabolism, 2013
- EGFR-Mediated Reactivation of MAPK Signaling Contributes to Insensitivity of BRAF-Mutant Colorectal Cancers to RAF Inhibition with VemurafenibCancer Discovery, 2012
- Multiple Endocrine Neoplasia Type 2B with a RET Proto-Oncogene A883F Mutation Displays a More Indolent Form of Medullary Thyroid Carcinoma Compared with a RET M918T MutationThyroid®, 2011
- Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium studyThe Lancet Oncology, 2010
- RETGenetic Screening in Patients with Medullary Thyroid Cancer and Their Relatives: Experience with 807 Individuals at One CenterJournal of Clinical Endocrinology & Metabolism, 2007
- Proximity of Chromosomal Loci That Participate in Radiation-Induced Rearrangements in Human CellsScience, 2000