Morphine suppression of ethanol withdrawal in mice
- 1 January 1976
- journal article
- Published by Springer Science and Business Media LLC in Cellular and Molecular Life Sciences
- Vol. 32 (1), 79-82
- https://doi.org/10.1007/bf01932634
Abstract
The acute administration of morphine, alcohol or dopamine results in a pronounced suppression of the convulsions produced by alcohol in mice. The suppressive action of morphine on alcohol withdrawal in the mouse apparently is not a product of morphine intoxication, but rather to some other specific interaction between alcohol and morphine in the central nervous system. The conclusion suggest that dopamine may play a significant role as a modulator in convulsions produced during alcohol withdrawal.Keywords
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