In vitro selection of RNA molecules that bind specific ligands
- 30 August 1990
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 346 (6287), 818-822
- https://doi.org/10.1038/346818a0
Abstract
Subpopulations of RNA molecules that bind specifically to a variety of organic dyes have been isolated from a population of random sequence RNA molecules. Roughly one in 1010 random sequence RNA molecules folds in such a way as to create a specific binding site for small ligands.Keywords
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