Trends in Lipids and Lipoproteins in US Adults, 1988-2010
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Open Access
- 17 October 2012
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 308 (15), 1545-1554
- https://doi.org/10.1001/jama.2012.13260
Abstract
Epidemiologic studies have demonstrated that high concentrations of low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) and low levels of high-density lipoprotein cholesterol (HDL-C) are major risk factors for coronary heart disease (CHD).1-6 Although triglyceride levels have not been shown to be an independent risk factor for CHD, there is increasing evidence of a strong association between elevated triglyceride levels and CHD risk.7,8 Very low-density lipoprotein cholesterol combined with LDL-C form non–HDL-C, which may enhance CHD risk prediction when triglyceride levels are high (200-499 mg/dL).9Keywords
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