Microsporidial Stromal Keratitis Masquerading as Acute Graft Rejection
- 1 March 2015
- journal article
- case report
- Published by Ovid Technologies (Wolters Kluwer Health) in Cornea
- Vol. 34 (3), 353-354
- https://doi.org/10.1097/ico.0000000000000337
Abstract
To describe the clinical features, disease course, management, and visual outcome of stromal microsporidial keratitis involving the corneal graft in an immunocompetent patient.Case report.We report the case of a 21-year-old immunocompetent woman, who underwent penetrating keratoplasty for advanced keratoconus in her right eye and presented with features of acute graft rejection after 15 months. Standard treatment using topical and systemic steroids failed to reverse the graft rejection. A regraft was performed in that eye. Histopathology of the donor corneal button revealed microsporidiosis involving the deep stroma.Microsporidiosis is rarely encountered in a corneal graft and masquerades as acute graft rejection. Histopathology could help in making a final diagnosis.Keywords
This publication has 9 references indexed in Scilit:
- Microsporidial Keratitis: Need for Increased AwarenessSurvey of Ophthalmology, 2011
- Microsporidia Evolved from Ancestral Sexual FungiCurrent Biology, 2008
- Microsporidia: A Review of 150 Years of ResearchThe Open Parasitology Journal, 2008
- Microsporidium Stromal Keratitis: In Vivo Confocal FindingsCornea, 2007
- Clinical and Microbiological Profile of Microsporidial Keratoconjunctivitis in Southern IndiaOphthalmology, 2006
- Chronic microsporidial stromal keratitis in an immunocompetent, non-contact lens wearerIndian Journal of Ophthalmology, 2005
- Corneal MicrosporidiosisOphthalmology, 1990
- Nosematosis of the CorneaAmerican Journal of Ophthalmology, 1981
- Encephalitozoonosis (nosematosis) of the cornea.British Journal of Ophthalmology, 1973