Frequency of occult high-grade squamous intraepithelial neoplasia and invasive cancer within anal condylomata in men who have sex with men.
Open Access
- 1 July 2010
- journal article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 51 (1), 107-110
- https://doi.org/10.1086/653426
Abstract
Human papillomavirus causes anal condylomata, high-grade anal intraepithelial neoplasia, and anal squamous cell cancer. We found high-grade intraepithelial neoplasia or squamous cell cancer in 75 (47%) of 159 HIV-seropositive men who have sex with men (MSM) and in 42 (26%) of 160 HIVseronegative MSM with anal condylomata meriting surgery (P<.001, determined by use of the χ2 test). Anal condylomata in MSM often harbor high-grade intraepithelial neoplasia and squamous cell cancer.Keywords
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