Novel Methodology to Determine the Accuracy of the OmniPod Insulin Pump: A Key Component of the Artificial Pancreas System
Open Access
- 1 November 2011
- journal article
- research article
- Published by SAGE Publications in Journal of Diabetes Science and Technology
- Vol. 5 (6), 1509-1518
- https://doi.org/10.1177/193229681100500627
Abstract
This article describes two novel and easy approaches for assessing the accuracy of insulin pumps as implemented within the Artificial Pancreas system. The approaches are illustrated by data testing the OmniPod Insulin Management System at its lowest delivery volume (0.05 U) and at doses of 0.1, 0.2, 1, and 6U. In method 1, a pipette, digital microscope, and imaging software were used to measure average bolus delivery on a linear scale for multiple volumes. In method 2, a digital microscope and imaging software were used to measure the volume of a spherical bolus of 0.05 U of insulin. Bench testing results using the two novel methods demonstrated that the OmniPod is extremely accurate, with a relative error ranging from −0.90% to +0.96% for all measured doses (0.05, 0.1, 0.2, 1, and 6 U). In method 1, at target bolus dose of 0.05 U, the mean delivered dose (± standard deviation) was 0.0497 ± 0.003 U, 0.099 ± 0.005 U at 0.1 U, 0.2 ± <1e-5 U at 0.2 U, 1.001 ± 0.018 U at 1 U, and 6.03 ± 0.04 U at 6 U. In method 2, at target bolus dose of 0.5 μl, the mean delivered dose for both OmniPods was 0.505 ± 0.014. Both methods confirmed a high degree of accuracy for the OmniPod insulin pump. These techniques can be used to estimate delivery volume in other infusion pumps as well.Keywords
This publication has 16 references indexed in Scilit:
- Retrospective Analysis and Patient Satisfaction Assessment of Insulin Pump Therapy in Patients with Type 2 DiabetesSouthern Medical Journal, 2011
- Insulin Pump Therapy in Patients with Type 2 Diabetes Safely Improved Glycemic Control Using a Simple Insulin Dosing RegimenDiabetes Technology & Therapeutics, 2010
- Using Insulin Pump Therapy in Poorly Controlled Type 2 DiabetesThe Diabetes Educator, 2010
- Siphon Effects on Continuous Subcutaneous Insulin Infusion Pump Delivery PerformanceJournal of Diabetes Science and Technology, 2010
- Modular Artificial β-Cell System: A Prototype for Clinical ResearchJournal of Diabetes Science and Technology, 2008
- Adolescent Use of Insulin and Patient-Controlled Analgesia Pump Technology: A 10-Year Food and Drug Administration Retrospective Study of Adverse EventsPEDIATRICS, 2008
- Insulin Pump Therapy in Youth With Type 1 Diabetes: A Retrospective Paired StudyPEDIATRICS, 2006
- Continuous Subcutaneous Insulin Infusion (CSII) of Insulin Aspart Versus Multiple Daily Injection of Insulin Aspart/Insulin Glargine in Type 1 Diabetic Patients Previously Treated With CSIIDiabetes Care, 2005
- Accuracy and Precision of Low-Dose Insulin Administration Using Syringes, Pen Injectors, and a PumpClinical Pediatrics, 2004
- The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes MellitusThe New England Journal of Medicine, 1993