Increased Nocturnal Blood Pressure in Enuretic Children With Polyuria
- 31 October 2009
- journal article
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal of Urology
- Vol. 182 (4S), 1954-1960
- https://doi.org/10.1016/j.juro.2009.04.079
Abstract
Purpose: We investigated the association between nocturnal blood pressure and urine production in children with enuresis. Materials and Methods: A total of 39 consecutive children with a mean age of 9.8 years (range 6.2 to 14.9) with monosymptomatic nocturnal enuresis completed a bladder diary, including 2 weeks of basic documentation and 2 with desmopressin titration from 120 to 240 μg sublingually. Arterial blood pressure was measured every 30 minutes during 24 hours and during 4 additional nights using an ambulatory blood pressure monitor. Furthermore, 10 healthy children were recruited into the study who completed a bladder diary for 5 days while measuring arterial blood pressures with documentation of all intake and voided volumes. Results: Patients with nocturnal polyuria had significantly higher nocturnal mean arterial pressure than patients without polyuria and controls (p <0.05). Furthermore, a positive correlation was seen between nocturnal urine output and nocturnal mean arterial pressure (r = 0.32, p <0.001). Nocturnal urine output was significantly higher during wet nights than dry nights (p <0.001). However, no significant difference was found in mean arterial pressure between wet and dry nights. Conclusions: Nocturnal mean arterial pressure was significantly higher in children with enuresis with polyuria than in children without polyuria. There was a significant positive correlation between average nocturnal mean arterial pressure and nocturnal urine volume in the whole study. The association between nocturnal blood pressure and urine volume, and the role of blood pressure should be investigated in a larger group of children with enuresis who have nocturnal polyuria.Keywords
This publication has 18 references indexed in Scilit:
- The Circadian Defect in Plasma Vasopressin and Urine Output is Related to Desmopressin Response and Enuresis Status in Children With Nocturnal EnuresisJournal of Urology, 2008
- Primary monosymptomatic nocturnal enuresis in children and adolescentsInternational Journal of Clinical Practice, 2007
- Nocturnal polyuria in monosymptomatic nocturnal enuresis refractory to desmopressin treatmentAmerican Journal of Physiology-Renal Physiology, 2006
- Nocturia and Circadian Blood Pressure Profile in Healthy Elderly Male VolunteersJournal of Urology, 2006
- The Standardization of Terminology of Lower Urinary Tract Function in Children and Adolescents: Report from the Standardisation Committee of the International Children’s Continence SocietyJournal of Urology, 2006
- Evaluation and management of hypertension in children and adolescents (part one): DiagnosisJournal of Pediatric Health Care, 2005
- THE EFFECT OF ALARM TREATMENT ON THE FUNCTIONAL BLADDER CAPACITY IN CHILDREN WITH MONOSYMPTOMATIC NOCTURNAL ENURESISJournal of Urology, 2004
- Nocturnal enuresisCurrent Opinion in Urology, 2002
- CHANGES IN NOCTURNAL BLADDER CAPACITY DURING TREATMENT WITH THE BELL AND PAD FOR MONOSYMPTOMATIC NOCTURNAL ENURESISJournal of Urology, 1998
- Estimating bladder capacity in childrenUrology, 1983