Identifying HAM‐A cutoffs for mild, moderate, and severe generalized anxiety disorder
- 18 August 2010
- journal article
- Published by Wiley in International Journal of Methods in Psychiatric Research
- Vol. 19 (4), 223-232
- https://doi.org/10.1002/mpr.323
Abstract
The aim of the current study was to identify and evaluate cutoffs for mild, moderate, and severe ranges of Hamilton Anxiety Rating Scale (HAM-A) scores. Data were from a four-week randomized trial of treatment for generalized anxiety disorder. Measures included the HAM-A, SF-36, Hospital Anxiety and Depression Scale (HADS), and Clinical Global Impressions of Severity (CGI-S) scale. HAM-A cutoffs were identified based on literature review, expert panel input, and MANOVA models. The optimal cutoff set was evaluated based on association with clinician CGI-S ratings. The sample included 144 patients (56.3% female; 73.6% white; mean age = 35.7 years; mean baseline HAM-A score = 23.7). The optimal HAM-A score ranges were: mild anxiety = 8-14; moderate = 15-23; severe ≥ 24 (scores ≤ 7 were considered to represent no/minimal anxiety). Analysis of variance (ANOVA) models found statistically significant differences among these groups in the SF-36 and HADS. The HAM-A severity ranges closely corresponded to clinicians' CGI-S ratings. The study represents the first step towards developing severity ranges for the HAM-A. These cutoffs should be used with caution and validated in larger samples. If the proposed cutoffs are accepted for general use, they could make results more meaningful and interpretable for researchers, clinicians, and patients.Keywords
This publication has 44 references indexed in Scilit:
- Estimation of symptom-free days in generalized anxiety disorderCurrent Medical Research and Opinion, 2006
- Identification of cut-points for mild, moderate and severe pain due to diabetic peripheral neuropathyPain, 2005
- Efficacy and Tolerability of Citalopram in the Treatment of Late-Life Anxiety Disorders: Results From an 8-Week Randomized, Placebo-Controlled TrialAmerican Journal of Psychiatry, 2005
- Paroxetine Treatment of Generalized Anxiety Disorder: A Double-Blind, Placebo-Controlled StudyAmerican Journal of Psychiatry, 2003
- Efficacy and Safety of Hydroxyzine in the Treatment of Generalized Anxiety DisorderBritish Journal of Psychology, 2002
- Venlafaxine Extended-ReleaseCNS Drugs, 2001
- The MOS 36-ltem Short-Form Health Survey (SF-36)Medical Care, 1992
- Generalized Anxiety or Depression Measured by the Hamilton Anxiety Scale and the Melancholia Scale in Patients before and after Cardiac SurgeryPsychopathology, 1984
- The Hospital Anxiety and Depression ScaleActa Psychiatrica Scandinavica, 1983
- The Assessment of Changes in Anxiety in a Drug Trial: A Comparison of MethodsThe British Journal of Psychiatry, 1968