Indazole- and Indole-5-carboxamides: Selective and Reversible Monoamine Oxidase B Inhibitors with Subnanomolar Potency
- 16 July 2014
- journal article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 57 (15), 6679-6703
- https://doi.org/10.1021/jm500729a
Abstract
No abstract availableKeywords
This publication has 95 references indexed in Scilit:
- Multi Target Neuroprotective and Neurorestorative Anti-Parkinson and Anti-Alzheimer Drugs Ladostigil and M30 Derived from RasagilineExperimental Neurobiology, 2013
- Investigational agents in the treatment of Parkinson's disease: focus on safinamideJournal of Experimental Pharmacology, 2012
- Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Antidiabetes DrugsACS Medicinal Chemistry Letters, 2011
- Moving beyond Rules: The Development of a Central Nervous System Multiparameter Optimization (CNS MPO) Approach To Enable Alignment of Druglike PropertiesACS Chemical Neuroscience, 2010
- Fast automated placement of polar hydrogen atoms in protein-ligand complexesJournal of Cheminformatics, 2009
- Inhibition of monoamine oxidase by (E)-styrylisatin analoguesBioorganic & Medicinal Chemistry Letters, 2009
- Monoamine oxidase inactivation: From pathophysiology to therapeuticsAdvanced Drug Delivery Reviews, 2008
- The influence of drug-like concepts on decision-making in medicinal chemistryNature Reviews Drug Discovery, 2007
- From a Parkinson's disease expert: Rasagiline and the Future of TherapyMolecular Neurodegeneration, 2007
- UCSF Chimera?A visualization system for exploratory research and analysisJournal of Computational Chemistry, 2004