Persistent Mitosis of Transfused Homologous Leukocytes in Children Receiving Antileukemic Therapy
- 6 December 1963
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 142 (3597), 1305-1311
- https://doi.org/10.1126/science.142.3597.1305
Abstract
Temporary homologous bone marrow grafts were observed in three patients with acute leukemia, receiving intensive antileukemic treatment, following transfusion of peripheral blood cells from donors with chronic myelocytic leukemia. Persistent mitosis of the transfused cells, containing the Philadelphia chromosome marker, were detected by cytogenetic techniques 19, 39, and 52 days after transfusion.Keywords
This publication has 7 references indexed in Scilit:
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- Chromosome Preparatons of Bone Marrow Cells without PriorIn VitroCulture orIn VivoColchicine AdministrationStain Technology, 1962
- Chromosome preparations of leukocytes cultured from human peripheral bloodExperimental Cell Research, 1960
- Prolonged Survival of a Bone-marrow Graft Resulting in a Blood-group ChimeraBMJ, 1960