Nutritional Consequences of Radiotherapy in Nasopharynx Cancer Patients
- 1 July 2004
- journal article
- Published by Taylor & Francis Ltd in Nutrition and Cancer
- Vol. 49 (2), 156-161
- https://doi.org/10.1207/s15327914nc4902_6
Abstract
Nasopharynx cancer (NPC) occurs frequently in southern China. Radiotherapy (RT) is the standard treatment for this cancer, and weight loss is commonly observed during and for a prolonged period after RT. The determinants of this phenomenon are not well known. The nutritional status of 38 NPC patients was assessed serially before and for a 6-mo period after RT. Body weight, body composition (by dual X-ray absorptiometry), basal metabolic rate (BMR, by indirect calorimetry), and calorie intake (by 3-day dietary record) were documented at pre-RT (T0), end-RT (T1), 2 mo post-end-RT (T2), and 6 mo post-end-RT (T3). The BMI at end-RT was 21.5 ± 3.7 kg/m2 (range = 13.7-27.9 kg/m2) and was significantly lower than that at pre-RT (P < 0.001). Body weight at T1-T3 was significantly lower than that at T0 (P < 0.001). Mean percentage weight loss was 10.8% at end-RT. Fifty-five percent of patients (20 of 30) had ≥10% weight loss by the end of RT. BMR corrected for body weight did not change significantly amo...Keywords
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