This article traces the “securitization” of U.S. foreign economic policy in the administration of George W. Bush. It does so with reference to U.S. economic policy in East and Southeast Asia. It argues that in the context of U.S. economic and military preponderance in the world order, the United States has been unable to resist the temptation to link foreign economic and security policy. While there was evidence of the securitization of economic globalization in U.S. policy from day one of the Bush administration, it was 9/11 that firmed up this trend. For the key members of the Bush foreign policy team, globalization is now seen not simply in neoliberal economic terms, but also through the lenses of the national security agenda of the United States. Economic globalization is now not only a benefit but also a “security problem.” The attacks on 9/11 offered the opportunity for what we might call the “unilateralist-idealists” in the Bush administration, to set in train their project for a post-sovereign approach to U.S. foreign policy.