Characterization of an Atypical γ-Secretase Complex from Hematopoietic Origin
- 23 February 2010
- journal article
- research article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 49 (13), 2796-2804
- https://doi.org/10.1021/bi901388t
Abstract
No abstract availableKeywords
This publication has 55 references indexed in Scilit:
- Modulation of γ-secretase specificity using small molecule allosteric inhibitorsProceedings of the National Academy of Sciences of the United States of America, 2009
- Gender- and Age-Dependent γ-Secretase Activity in Mouse Brain and Its Implication in Sporadic Alzheimer DiseasePLOS ONE, 2009
- Pen2 and Presenilin-1 Modulate the Dynamic Equilibrium of Presenilin-1 and Presenilin-2 γ-Secretase ComplexesJournal of Biological Chemistry, 2009
- TMP21 is a presenilin complex component that modulates γ-secretase but not ɛ-secretase activityNature, 2006
- Presenilin endoproteolysis is an intramolecular cleavageMolecular and Cellular Neuroscience, 2005
- APH-1a Is the Principal Mammalian APH-1 Isoform Present in γ-Secretase Complexes during Embryonic DevelopmentJournal of Neuroscience, 2005
- Regulated Hyperaccumulation of Presenilin-1 and the “γ-Secretase” ComplexPublished by Elsevier BV ,2003
- In Vitro Characterization of the Presenilin-Dependent γ-Secretase Complex Using a Novel Affinity LigandBiochemistry, 2003
- Presenilin-1 and Presenilin-2 Exhibit Distinct yet Overlapping γ-Secretase ActivitiesJournal of Biological Chemistry, 2003
- L-685,458, an Aspartyl Protease Transition State Mimic, Is a Potent Inhibitor of Amyloid β-Protein Precursor γ-Secretase ActivityBiochemistry, 2000