Odontogenic myxoma: An updated analysis of 1,692 cases reported in the literature
- 23 April 2018
- journal article
- review article
- Published by Wiley in Oral Diseases
- Vol. 25 (3), 676-683
- https://doi.org/10.1111/odi.12875
Abstract
Objective To integrate the available data published on odontogenic myxoma (OM) into a comprehensive analysis of its clinical/radiologic features. Methods Electronic search undertaken in January/2018, looking for publications reporting cases of OM. Results 377 publications included. We identified 1692 lesions and 695 were used for analysis of recurrence. There is predominance of OMs in females and in mandibles. OMs usually present with bone expansion, asymptomatic cortical perforation, multilocular. Lesion location (maxilla/mandible), bone expansion, cortical bone perforation, locular radiological appearance, tooth resorption, odontogenic epithelial rests or angular septa are not associated with recurrence. While curettage (31.3%) showed the highest recurrence rate, marginal resection (1.3%) and segmental resection (3.1%) showed the lowest values. Enucleation + peripheral osteotomy (6.7%) showed better results than enucleation (13.1%) or enucleation + curettage (12.7%). In comparison to unilocular lesions, multilocular ones were significantly more prevalent in mandibles, more often presented expansion and cortical bone perforation, had larger mean size, and were more often treated by segmental resection. Conclusion Conservative surgical procedures are associated with higher probability of recurrence of OM. Taking into consideration the recurrence rate and morbidity associated with different surgical treatments, tumor enucleation followed by peripheral osteotomy should be considered as the first therapeutic choice.This publication has 10 references indexed in Scilit:
- Gingival cyst of the adult, lateral periodontal cyst, and botryoid odontogenic cyst: An updated systematic reviewOral Diseases, 2018
- Glandular odontogenic cyst: An updated analysis of 169 cases reported in the literatureOral Diseases, 2017
- Peripheral calcifying cystic odontogenic tumour and peripheral dentinogenic ghost cell tumour: an updated systematic review of 117 cases reported in the literatureActa Odontologica Scandinavica, 2016
- Odontogenic myxoma: Clinico-pathological, immunohistochemical and ultrastructural findings of a multicentric seriesOral Oncology, 2008
- Odontogenic myxoma: review of the literature and report of 30 cases from South AfricaOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2007
- Odontogenic Myxoma: A Clinicopathologic Study of 25 CasesArchives of Pathology & Laboratory Medicine, 2006
- Myxoma of the mandibular condyleOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2000
- Malignant odontogenic myxoma of the maxilla: case with cytogenetic confirmationThe Journal of Laryngology & Otology, 2000
- Myxomas of Soft Tissues and the Facial SkeletonAnnals of Otology, Rhinology & Laryngology, 1987