HEART-LIVER TRANSPLANTATION IN A PATIENT WITH FAMILIAL HYPERCHOLESTEROLAEMIA
Open Access
- 1 June 1984
- journal article
- case report
- Published by Elsevier BV in The Lancet
- Vol. 323 (8391), 1382-1383
- https://doi.org/10.1016/s0140-6736(84)91876-2
Abstract
A girl aged 6 years 9 months with severe heart disease secondary to homozygous familial hypercholesterolaemia underwent orthotopic cardiac transplantation and her liver was replaced with the liver of the same donor. In the first 10 weeks after transplantation serum cholesterol fell to 270 mg/dl from preoperative concentrations of more than 1000 mg/dl.Keywords
This publication has 8 references indexed in Scilit:
- Characterization of hepatic low density lipoprotein binding and cholesterol metabolism in normal and homozygous familial hypercholesterolemic subjects.JCI Insight, 1984
- Portacaval Shunt in Patients with Familial HypercholesterolemiaAnnals of Surgery, 1983
- Defective Lipoprotein Receptors and AtherosclerosisNew England Journal of Medicine, 1983
- Evolution of Liver TransplantationHepatology, 1982
- Delayed clearance of very low density and intermediate density lipoproteins with enhanced conversion to low density lipoprotein in WHHL rabbits.Proceedings of the National Academy of Sciences of the United States of America, 1982
- Multilayer film elements for clinical analysis: applications to representative chemical determinations.Clinical Chemistry, 1978
- Genetic heterogeneity in familial hypercholesterolemia: evidence for two different mutations affecting functions of low-density lipoprotein receptor.Proceedings of the National Academy of Sciences of the United States of America, 1975
- Enzymatic Determination of Total Serum CholesterolClinical Chemistry, 1974