RNA N6-Methyladenosine Methyltransferase METTL3 Facilitates Colorectal Cancer by Activating the m6A-GLUT1-mTORC1 Axis and Is a Therapeutic Target
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Open Access
- 1 March 2021
- journal article
- research article
- Published by Elsevier BV in Gastroenterology
- Vol. 160 (4), 1284-1300.e16
- https://doi.org/10.1053/j.gastro.2020.11.013
Abstract
No abstract availableThis publication has 45 references indexed in Scilit:
- mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and RapamycinScience, 2013
- Comprehensive molecular characterization of human colon and rectal cancerNature, 2012
- Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop CodonsCell, 2012
- A unifying model for mTORC1-mediated regulation of mRNA translationNature, 2012
- The translational landscape of mTOR signalling steers cancer initiation and metastasisNature, 2012
- Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian ProteomesCell, 2011
- Ultrafast and memory-efficient alignment of short DNA sequences to the human genomeGenome Biology, 2009
- Phosphorylation of ribosomal p70 S6 kinase and rapamycin sensitivity in human colorectal cancerCancer Letters, 2007
- Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profilesProceedings of the National Academy of Sciences of the United States of America, 2005
- Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signalingGenes & Development, 2003