MirSNP, a database of polymorphisms altering miRNA target sites, identifies miRNA-related SNPs in GWAS SNPs and eQTLs
Open Access
- 23 November 2012
- journal article
- Published by Springer Science and Business Media LLC in BMC Genomics
- Vol. 13 (1), 661
- https://doi.org/10.1186/1471-2164-13-661
Abstract
Numerous single nucleotide polymorphisms (SNPs) associated with complex diseases have been identified by genome-wide association studies (GWAS) and expression quantitative trait loci (eQTLs) studies. However, few of these SNPs have explicit biological functions. Recent studies indicated that the SNPs within the 3’UTR regions of susceptibility genes could affect complex traits/diseases by affecting the function of miRNAs. These 3’UTR SNPs are functional candidates and therefore of interest to GWAS and eQTL researchers.This publication has 41 references indexed in Scilit:
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