Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo*
- 1 November 1995
- journal article
- clinical trial
- Published by Springer Science and Business Media LLC in Clinical Pharmacology & Therapeutics
- Vol. 58 (5), 556-566
- https://doi.org/10.1016/0009-9236(95)90176-0
Abstract
No abstract availableKeywords
This publication has 31 references indexed in Scilit:
- The use of cimetidine to reduce dapsone‐dependent methaemoglobinaemia in dermatitis herpetiformis patients.British Journal of Clinical Pharmacology, 1992
- The effect of preincubation with cimetidine on the N‐hydroxylation of dapsone by human liver microsomes.British Journal of Clinical Pharmacology, 1991
- Oral Therapy forPneumocystis cariniiPneumonia in the Acquired Immunodeficiency SyndromeNew England Journal of Medicine, 1990
- Dapsone, Trimethoprim, and Sulfamethoxazole Plasma Levels during Treatment of Pneumocystis Pneumonia in Patients with the Acquired Immunodeficiency Syndrome (AIDS)Annals of Internal Medicine, 1989
- New Approaches to Chemotherapy for LeprosyDrugs, 1983
- Pharmacokinetic observations on dapsone in dermatitis herpetiformisBritish Journal of Dermatology, 1983
- Leprosy TodayNew England Journal of Medicine, 1982
- Microsomal N-Oxidation of Dapsone as a Cause of Methemoglobin Formation in Human Red Cells *The American Journal of Tropical Medicine and Hygiene, 1972
- Mechanism of methemoglobin formation by diphenylsulfones: Effect of 4-Amino-4′-hydroxyaminodiphenylsulfone and other p-substituted derivativesBiochemical Pharmacology, 1972
- Biochemical effects of aromatic amines-I. Methaemoglobinaemia, haemolysis and heinz-body formation induced by 4,4′-diaminodiphenylsulphoneBiochemical Pharmacology, 1965