Adrenocorticotropin-Cortisol Axis Abnormalities in Hemodialysis Patients*
- 1 January 1979
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 48 (1), 92-95
- https://doi.org/10.1210/jcem-48-1-92
Abstract
The ACTH-cortisol axis was studied in 15 hemodialysis patients. Basal plasma cortisol concentrations were found to be elevated and ACTH to be in the high normal range. Cortisol responded normally to exogenous ACTH, but neither cortisol nor ACTH were suppressed in response to oral dexamethasone. 11-Deoxycortisol and ACTH concentrations did not rise normally in response to either oral or iv metyrapone. We conclude that standard testing of the ACTH-cortisol axis in dialysis patients yields results suggesting Cushing's syndrome.Keywords
This publication has 2 references indexed in Scilit:
- Thyroid Abnormalities in Renal FailureAnnals of Internal Medicine, 1973
- Data on Transcortin Activity in Human Plasma as Studied by Gel FiltrationJournal of Clinical Endocrinology & Metabolism, 1966