Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria
Open Access
- 13 March 2007
- journal article
- review article
- Published by The Royal Society in Philosophical Transactions B
- Vol. 362 (1483), 1165-1183
- https://doi.org/10.1098/rstb.2007.2042
Abstract
Quorum sensing describes the ability of bacteria to sense their population density and respond by modulating gene expression. In the plant soft-rotting bacteria, such as Erwinia , an arsenal of plant cell wall-degrading enzymes is produced in a cell density-dependent manner, which causes maceration of plant tissue. However, quorum sensing is central not only to controlling the production of such destructive enzymes, but also to the control of a number of other virulence determinants and secondary metabolites. Erwinia synthesizes both N -acylhomoserine lactone (AHL) and autoinducer-2 types of quorum sensing signal, which both play a role in regulating gene expression in the phytopathogen. We review the models for AHL-based regulation of carbapenem antibiotic production in Erwinia . We also discuss the importance of quorum sensing in the production and secretion of virulence determinants by Erwinia , and its interplay with other regulatory systems.Keywords
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