Host Factors Impact Vaccine Efficacy: Implications for Seasonal and Universal Influenza Vaccine Programs
- 1 November 2019
- journal article
- review article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 93 (21)
- https://doi.org/10.1128/jvi.00797-19
Abstract
Influenza is a global public health problem. Current seasonal influenza vaccines have highly variable efficacy, and thus attempts to develop broadly protective universal influenza vaccines with durable protection are under way. While much attention is given to the virus-related factors contributing to inconsistent vaccine responses, host-associated factors are often neglected.Keywords
Funding Information
- HHS | NIH | National Institute of Allergy and Infectious Diseases (HHS N272201400007C)
- HHS | NIH | National Institute on Aging (U54AG062333)
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