Selection of adequate optimization criteria in chromatographic separations
Open Access
- 19 March 2009
- journal article
- Published by Springer Science and Business Media LLC in Analytical and Bioanalytical Chemistry
- Vol. 394 (5), 1283-1289
- https://doi.org/10.1007/s00216-009-2709-9
Abstract
Computer-assisted optimization of chromatographic separations is still a fruitful activity. In fact, advances in computerized data handling should make the application of systematic optimization strategies much easier. However, in most contemporary applications, the optimization criterion is not considered to be a key issue (Vanbel, J Pharm Biomed , 21:603–610, 1999 ). In this paper, an update of the importance of selecting adequate criteria in chromatographic separation is presented.Keywords
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