Colonic necrosis following sodium polystyrene sulfonate (Kayexalate®)-sorbitol enema in a renal transplant patient
- 1 June 1993
- journal article
- case report
- Published by Ovid Technologies (Wolters Kluwer Health) in Diseases of the Colon & Rectum
- Vol. 36 (6), 607-609
- https://doi.org/10.1007/bf02049870
Abstract
The authors present the case of a patient who developed near total colonic necrosis shortly after renal transplantation. The onset of symptoms was temporally related to the administration of sodium polystyrene (Kayexalate; Sanofi Winthrop Pharmaceuticals, New York, NY)-sorbitol enemas for treatment of hyperkalemia. Three similar cases have been reported in the literature. The presence of uremia and the use of sorbitol appear to be common denominators in the pathophysiology of this complication. It is suggested that Kayexalate-sorbitol enemas be avoided in renal transplant patients.Keywords
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