Agonist-independent Gαz activity negatively regulates beta-cell compensation in a diet-induced obesity model of type 2 diabetes
Open Access
- 1 January 2021
- journal article
- research article
- Published by Elsevier BV in Online Journal of Public Health Informatics
- Vol. 296, 100056
- https://doi.org/10.1074/jbc.ra120.015585
Abstract
No abstract availableKeywords
Funding Information
- U.S. Department of Veterans Affairs (I01 BX00370)
- U.S. Department of Veterans Affairs (I01 BX004031)
- HHS | NIH | Office of Extramural Research, National Institutes of Health (K01 DK080845)
- HHS | NIH | Office of Extramural Research, National Institutes of Health (R01 DK102598)
- HHS | NIH | Office of Extramural Research, National Institutes of Health (R01 AG056771)
- HHS | NIH | Office of Extramural Research, National Institutes of Health (T32-AG-000213)
- American Society for Pharmacology and Experimental Therapeutics (ASPET SURF)
- American Federation for Aging Research (AFAR Research Grant)
- American Diabetes Association (1-14-BS-115)
This publication has 46 references indexed in Scilit:
- Deletion of GαZ Protein Protects against Diet-induced Glucose Intolerance via Expansion of β-Cell MassOnline Journal of Public Health Informatics, 2012
- Rap1 Promotes Multiple Pancreatic Islet Cell Functions and Signals through Mammalian Target of Rapamycin Complex 1 to Enhance ProliferationOnline Journal of Public Health Informatics, 2010
- Progression of Diet-Induced Diabetes in C57BL6J Mice Involves Functional Dissociation of Ca2+ Channels From Secretory VesiclesDiabetes, 2010
- Gene ontology analysis for RNA-seq: accounting for selection biasGenome Biology, 2010
- Molecular biology of histidine decarboxylase and prostaglandin receptorsProceedings of the Japan Academy, Series B, 2010
- Chronic Palmitate Exposure Inhibits Insulin Secretion by Dissociation of Ca2+ Channels from Secretory GranulesCell Metabolism, 2009
- Pancreatic islet dysfunction in type 2 diabetes: a rational target for incretin-based therapiesCurrent Medical Research and Opinion, 2007
- Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray ExperimentsStatistical Applications in Genetics and Molecular Biology, 2004
- Prostaglandin E receptor EP3γ isoform, with mostly full constitutive Gi activity and agonist‐dependent Gs activityFEBS Letters, 1996
- Hypothesis: Prostaglandins mediate defective glucose recognition in diabetes mellitusProstaglandins and Medicine, 1980