IL-6 levels are dramatically high in the sputum from children with sickle cell disease during acute chest syndrome
Open Access
- 11 December 2020
- journal article
- research article
- Published by American Society of Hematology in Blood Advances
- Vol. 4 (24), 6130-6134
- https://doi.org/10.1182/bloodadvances.2020003519
Abstract
Sputum interleukin-6 (IL-6) level is high during acute chest syndrome (ACS) in pediatric sickle cell disease, supporting anti–IL-6 trials. Sputum IL-8, CCL2, and CCL3 levels are also high during ACS, possibly contributing to recruitment of inflammatory cells in the lungs.This publication has 19 references indexed in Scilit:
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