Evaluating and comparing immunostaining and computational methods for spatial profiling of drug response in patient-derived explants
- 13 December 2020
- journal article
- research article
- Published by Elsevier BV in Laboratory Investigation
- Vol. 101 (3), 396-407
- https://doi.org/10.1038/s41374-020-00511-3
Abstract
No abstract availableFunding Information
- Cancer Research UK (C10604/A25151)
- RCUK | Medical Research Council
- Breast Cancer Now (2017NOVPCC1066)
This publication has 25 references indexed in Scilit:
- Proliferation assessment in breast carcinomas using digital image analysis based on virtual Ki67/cytokeratin double stainingBreast Cancer Research and Treatment, 2016
- Digital image analysis outperforms manual biomarker assessment in breast cancerLaboratory Investigation, 2016
- Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneityNature Communications, 2015
- Multiplexed immunohistochemistry, imaging, and quantitation: A review, with an assessment of Tyramide signal amplification, multispectral imaging and multiplex analysisMethods, 2014
- Objective Quantification of the Ki67 Proliferative Index in Neuroendocrine Tumors of the Gastroenteropancreatic SystemThe American Journal of Surgical Pathology, 2012
- ImmunoRatio: a publicly available web application for quantitative image analysis of estrogen receptor (ER), progesterone receptor (PR), and Ki-67Breast Cancer Research, 2010
- Multiple immunofluorescence labelling of formalin-fixed paraffin-embedded (FFPE) tissueBMC Cell Biology, 2008
- Ex vivo assessment of chemotherapy-induced apoptosis and associated molecular changes in patient tumor samples.2006
- Cytokeratins in normal lung and lung carcinomasVirchows Archiv B Cell Pathology Including Molecular Pathology, 1984
- A New Biometrical Procedure for Testing the Equality of Measurements from Two Different Analytical Methods. Application of linear regression procedures for method comparison studies in Clinical Chemistry, Part Icclm, 1983