Automated Insulin Delivery Algorithms
Open Access
- 1 August 2019
- journal article
- Published by American Diabetes Association in Diabetes Spectrum
- Vol. 32 (3), 209-214
- https://doi.org/10.2337/ds18-0100
Abstract
IN BRIEF Automated insulin delivery (AID; also known as artificial pancreas) has improved the regulation of blood glucose concentrations, reduced the frequency of hyperglycemic and hypoglycemic episodes, and improved the quality of life of people with diabetes and their families. Three different types of algorithms—proportional-integral-derivative control, model predictive control, and fuzzy-logic knowledge-based systems—have been used in AID control systems. This article will highlight the foundations of these algorithms and discuss their strengths and limitations. Multivariable artificial pancreas and dual-hormone (insulin and glucagon) systems will be introduced.Keywords
This publication has 27 references indexed in Scilit:
- Outpatient overnight glucose control with dual-hormone artificial pancreas, single-hormone artificial pancreas, or conventional insulin pump therapy in children and adolescents with type 1 diabetes: an open-label, randomised controlled trialThe Lancet Diabetes & Endocrinology, 2015
- Pathway to Artificial Pancreas Systems Revisited: Moving DownstreamDiabetes Care, 2015
- Outpatient Glycemic Control with a Bionic Pancreas in Type 1 DiabetesThe New England Journal of Medicine, 2014
- Automated Control of an Adaptive Bihormonal, Dual-Sensor Artificial Pancreas and Evaluation During Inpatient StudiesIEEE Transactions on Biomedical Engineering, 2014
- An Integrated Multivariable Artificial Pancreas Control SystemJournal of Diabetes Science and Technology, 2014
- Night glucose control with MD-Logic artificial pancreas in home setting: a single blind, randomized crossover trial-interim analysisPediatric Diabetes, 2013
- Fully Integrated Artificial Pancreas in Type 1 DiabetesDiabetes, 2012
- The Effect of Insulin Feedback on Closed Loop Glucose ControlJournal of Clinical Endocrinology & Metabolism, 2011
- Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trialThe Lancet, 2010
- An Artificial Endocrine PancreasDiabetes, 1974