Influenza Myopericarditis and Pericarditis: A Literature Review
Open Access
- 15 July 2022
- journal article
- review article
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 11 (14), 4123
- https://doi.org/10.3390/jcm11144123
Abstract
Myopericarditis is a rare complication of influenza infection. The presentation may range from mild and frequently unrecognized, to fulminant and potentially complicated by cardiogenic and/or obstructive shock (tamponade), which is associated with high mortality. We performed a review of literature on all influenza pericarditis and myopericarditis cases according to PRISMA guidelines using the PubMed search engine of the Medline database. Seventy-five cases of influenza myopericarditis and isolated pericarditis were identified from 1951 to 2021. Influenza A was reported twice as often as influenza B; however, influenza type did not correlate with outcome. Men and elderly patients were more likely to have isolated pericarditis, while women and younger patients were more likely to have myopericarditis. All included patients had pericardial effusion, while 36% had tamponade. Tamponade was more common in those with isolated pericarditis (41.2%) than myopericarditis (13.8%). Cardiogenic shock was more common in patients with myopericarditis (64%), with an overall mortality rate of 14.7%. Nearly 88% of the recovered patients remained without long-term complications reported. Conclusion: Influenza A appears a more common cause of pericarditis and myopericarditis. Isolated pericarditis was more commonly associated with tamponade but without reported deaths, whereas myopericarditis was more commonly associated with cardiogenic shock and death (19%).Keywords
This publication has 113 references indexed in Scilit:
- The cardiovascular manifestations of influenza: A systematic reviewInternational Journal of Cardiology, 2013
- Myopericarditis and exertional rhabdomyolysis following an influenza A (H3N2) infectionBMC Infectious Diseases, 2013
- Myocarditis Associated with Influenza A H1N1pdm2009Influenza Research and Treatment, 2012
- Influenza Myocarditis and Myositis: Case Presentation and Review of the LiteratureCanadian Journal of Cardiology, 2011
- Successful management of fulminant influenza A subtype H1N1 myocarditisBMJ Case Reports, 2010
- Cardiac Tamponade and Heart Failure Due to Myopericarditis as a Presentation of Infection with the Pandemic H1N1 2009 Influenza A VirusJournal of Clinical Microbiology, 2010
- Fulminant Myocarditis Due to H1N1 InfluenzaCirculation: Heart Failure, 2010
- Constrictive Pericarditis Accompanied by Swine-Origin Influenza A (H1N1) InfectionKorean Circulation Journal, 2010
- Case 9-2004The New England Journal of Medicine, 2004
- Postviral myopericarditis associated with the influenza virus: Report of eight cases∗The American Journal of Cardiology, 1959