Neuroimaging Findings in Patients with COVID-19
- 1 August 2020
- journal article
- research article
- Published by American Society of Neuroradiology (ASNR) in American Journal of Neuroradiology
- Vol. 41 (8), 1380-1383
- https://doi.org/10.3174/ajnr.A6630
Abstract
Little is known about the neurologic sequelae of coronavirus disease 2019 (COVID-19). We assessed neuroimaging findings in 4 patients positive for COVID-19. All had abnormal mental status, deranged coagulation parameters, and markedly elevated D-dimer levels. CT/MR imaging showed a common pattern of multifocal subcortical/cortical petechial-type hemorrhages, while SWI showed more extensive multifocal abnormalities. The appearances are consistent with a thrombotic microangiopathy and may be due to the heightened level of thrombosis in patients with COVID-19.This publication has 18 references indexed in Scilit:
- COVID-19: consider cytokine storm syndromes and immunosuppressionThe Lancet, 2020
- Sepsis-Induced Coagulopathy and Disseminated Intravascular CoagulationSeminars in Thrombosis and Hemostasis, 2020
- Comparison of a new criteria for sepsis-induced coagulopathy and International Society on Thrombosis and Haemostasis disseminated intravascular coagulation score in critically ill patients with sepsis 3.0: a retrospective studyBlood Coagulation & Fibrinolysis, 2018
- Critical Illness–Associated Cerebral MicrobleedsStroke, 2017
- Diffuse Cerebral Microbleeds after Extracorporeal Membrane Oxygenation SupportAmerican Journal of Respiratory and Critical Care Medicine, 2015
- Failure of Anticoagulant ThromboprophylaxisCritical Care Medicine, 2015
- Neurological Injury in Adults Treated With Extracorporeal Membrane OxygenationArchives of Neurology, 2011
- Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus InfectionCell, 2011
- Endothelial Function and DysfunctionCirculation, 2007
- Effect of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Receptor Blockers on Cardiac Angiotensin-Converting Enzyme 2Circulation, 2005