Synthesis and reduction reaction of novel triazole compounds in the solid-media condition by using microwave method
Open Access
- 31 December 2012
- journal article
- Published by European Journal of Chemistry in European Journal of Chemistry
- Vol. 3 (4), 442-446
- https://doi.org/10.5155/eurjchem.3.4.442-446.691
Abstract
Some new triazole-3-one compounds have been synthesized and then reduction of carbonyl group in the molecule has been carried out to give a corresponding hydroxyl group which possesses asymmetric carbon atom in good yields, short reaction times and an eco-friendly approach in solvent-free condition by using microwave irradiation.Keywords
This publication has 10 references indexed in Scilit:
- Microwave-assisted synthesis and antifungal activity of some new 1H-1,2,4-triazole derivativesRussian Journal of Organic Chemistry, 2008
- Synthesis of 4-Amino-4,5-dihydro-1H-1,2,4-triazole-5-ones and their Isatin-3-imine DerivativesMolecules, 2005
- Controlled Microwave Heating in Modern Organic SynthesisAngewandte Chemie, 2004
- Microwave assisted organic synthesis—a reviewTetrahedron, 2001
- Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approachBioorganic & Medicinal Chemistry Letters, 2001
- Solvent-free organic synthesesGreen Chemistry, 1999
- Microwave-assisted reduction of carbonyl compounds in solid state using sodium borohydride supported on aluminaTetrahedron Letters, 1997
- Sodium borohydride-amberlyst-15 (H+): An effective reductor for hindered and unreactive ketones in aprotic solventTetrahedron Letters, 1997
- Synthesis and antiviral activity of some new 1H-1,2,4-triazole derivativesEuropean Journal of Medicinal Chemistry, 1994
- Synthesis of new derivatives of 4‐amino‐2,4‐dihydro‐1,2,4‐triazol‐3‐one as potential antibacterial agentsJournal of Heterocyclic Chemistry, 1984