Focal Segmental Glomerulosclerosis with Sjogren Syndrome: A Case Report
Open Access
- 7 March 2021
- journal article
- Published by Turkish Journal of Internal Medicine in Turkish Journal of Internal Medicine
- Vol. 3 (Supplement), 107-109
- https://doi.org/10.46310/tjim.876204
Abstract
Sjogren's syndrome (SjS) is a chronic, slow-progressing, autoimmune and lymphoproliferative disease. The main symptoms of the syndrome are xerostomia and keratoconjuctivitis sicca as a result of chronic inflammatory infiltration of the salivary and lacrimal glands. Focal Segmental Glomerulosclerosis complicating primary Sjögren's syndrome is extremely rare. We report on a 39-year-old woman with 5 years history of sjogren syndrome who was found to have nephrotic syndrome. Histopathological findings in kidney biopsy compatible with focal segmental glomerulosclerosis. Steroid therapy was initiated (oral prednisolone at a dose of 15 mg/day) and Cyclosporine 2 * 100mg/d. FSGS, which is associated with sjögren's syndrome, was considered suitable for the presentation because of its rare occurrenceKeywords
This publication has 8 references indexed in Scilit:
- Nephrotic Syndrome due to Focal Segmental Glomerulosclerosis Complicating Sjögren's Syndrome: A Case Report and Literature Review.Case Reports in Rheumatology, 2019
- Renal involvement in primary Sjögren's syndrome: A retrospective study of 103 biopsy‐proven cases from a single center in ChinaInternational Journal of Rheumatic Diseases, 2017
- A multicentre study of 95 biopsy-proven cases of renal disease in primary Sjögren’s syndromeRheumatology, 2016
- Kidney biopsy findings in primary Sjögren syndromeNephrology Dialysis Transplantation, 2015
- Clinically Significant Renal Involvement in Primary Sjögren's Syndrome: Clinical Presentation and OutcomeArthritis & Rheumatism, 2013
- The complexity of Sjögren's syndrome: Novel aspects on pathogenesisImmunology Letters, 2011
- Renal Involvement in Primary Sjögren's SyndromeClinical Journal of the American Society of Nephrology, 2009
- Pathologic classification of focal segmental glomerulosclerosis: a working proposalAmerican Journal of Kidney Diseases, 2004