An update on imaging of Paget's sarcoma
- 30 June 2021
- journal article
- review article
- Published by Springer Science and Business Media LLC in Skeletal Radiology
- Vol. 50 (7), 1275-1290
- https://doi.org/10.1007/s00256-020-03682-8
Abstract
Paget's sarcoma is a rare and particularly aggressive tumour arising within pagetic bone, affecting approximately 1% of patients with Paget's disease during the course of their disease. Most of these tumours are osteosarcomas, but the age profile, skeletal distribution and clinical outcomes differ considerably from conventional osteosarcoma. In this review, we outline the clinical, radiographic/CT, scintigraphic and magnetic resonance imaging features of Paget's sarcoma. We also review the neoplastic and non-neoplastic mimics of Paget's sarcoma that should be considered in the differential diagnosis when encountering an aggressive lesion within pagetic bone.Keywords
This publication has 66 references indexed in Scilit:
- Imaging of Paget Disease of Bone and Its Musculoskeletal Complications: ReviewAmerican Journal of Roentgenology, 2011
- The Role of Surgery and Adjuvants to Survival in Pagetic OsteosarcomaClinical Orthopaedics and Related Research, 2010
- Lymphatic spread of pagetic osteogenic sarcoma detected by bone scanCancer Imaging, 2008
- The spine in Paget’s diseaseSkeletal Radiology, 2007
- Osteosarcoma in Paget's Disease of BoneJournal of Bone and Mineral Research, 2006
- A fatal case of pleural osteosarcoma mimicking mesothelioma in Paget's disease of boneRheumatology, 2003
- Familial Incidence of Paget??s Disease and Secondary Osteogenic SarcomaClinical Orthopaedics and Related Research, 1991
- Metastases of Carcinoma in the Pagetic BoneClinical Orthopaedics and Related Research, 1988
- Solitary renal cell carcinoma metastasis in Paget's disease simulating sarcomatous degenerationAmerican Journal of Roentgenology, 1977
- PAGET'S DISEASE OF BONE: INCIDENCE AND SUBCLINICAL FORMSThe Lancet, 1956