Patient Age and Long-term Survival in Colorectal Cancer Patients Who Undergo Emergency Surgery
- 30 January 2021
- journal article
- research article
- Published by Anticancer Research USA Inc. in Anticancer Research
- Vol. 41 (2), 1069-1076
- https://doi.org/10.21873/anticanres.14864
Abstract
Background/Aim: Emergency surgery for colorectal cancer (CRC) is a high-risk procedure with high morbidity and mortality rates, especially for older patients. The relationship between patient age status and long-term outcomes is unclear. We hypothesize that patient age might be associated with long-term outcomes in patients with CRC who undergo emergency surgery. Patients and Methods: Utilizing a database of CRC patients who received emergency surgery, we examined the prognostic association of patient age. Results: The ≥80-years group was significantly associated with American Society of Anesthesiologists (ASA) physical status, bowel obstruction, N stage, shorter operating time, and less adjuvant chemotherapy (all p<0.03); and also, with shorter recurrence-free survival [multivariable hazard ratio, 2.79; 95% confidence interval, 1.13-7.21; p=0.026]. ASA status and adjuvant chemotherapy were significantly associated with recurrence-free survival (all p<0.03). Conclusion: Advanced age is associated with shorter recurrence-free survival in CRC patients who undergo emergency surgery.Keywords
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