Osteoporosis evaluation through full developed speckle imaging
- 10 April 2020
- journal article
- research article
- Published by Wiley in Journal of Biophotonics
- Vol. 13 (7), e202000025
- https://doi.org/10.1002/jbio.202000025
Abstract
Osteoporosis is a disease characterized by Bone Mineral Density (BMD) reduction, weakening the bone structure. Its diagnosis is performed using ionizing radiation, increasing health risk. Optical techniques are safer, due to non‐ionizing radiation use, but limited to the analyses of bone tissue. This limitation may be circumvented in the oral cavity. In this work we explored the use of Laser Speckle Imaging (LSI) to differentiate the sound and osteoporotic maxilla and mandible bones in an in vitro model. Osteoporosis lesions were simulated with acid attack. The samples were evaluated by optical profilometry and LSI, using a custom software. Two image parameters were evaluated, speckle contrast ration and patches ratio. With the speckle contrast ratio, it was possible to differentiate sound from osteoporotic tissue. From speckle patches ratio it was observed a negative correlation with the roughness parameter. LSI is a promissory technique for assessment of osteoporosis lesions on alveolar bone.Keywords
Funding Information
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (PROCAD 88881.068505/2014‐01)
- Fundação de Amparo à Pesquisa do Estado de São Paulo (2017/21851‐0, 2017/21887‐4)
This publication has 22 references indexed in Scilit:
- OsteoporosisMedical Clinics of North America, 2015
- Laser Speckle Imaging: A Novel Method for Detecting Dental ErosionPLOS ONE, 2015
- The clinical diagnosis of osteoporosis: a position statement from the National Bone Health Alliance Working GroupOsteoporosis International, 2014
- A method to develop an in vitro osteoporosis model of porcine vertebrae: histological and biomechanical studyJournal of Neurosurgery: Spine, 2011
- Laser speckle contrast imaging in biomedical opticsJournal of Biomedical Optics, 2010
- Optics of surface disordered systemsThe European Physical Journal Special Topics, 2010
- You don't know what you don't knowOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2005
- Age and trabecular features of alveolar bone associated with osteoporosisOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2005
- Analysis of speckle images to assess surface roughnessOptics & Laser Technology, 2004
- Roughness parametersJournal of the American Academy of Dermatology, 2002