Drug Distribution in Living Cells via Label-Free Molecular Fingerprint
- 25 March 2020
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 63 (7), 3472-3474
- https://doi.org/10.1021/acs.jmedchem.0c00392
Abstract
A new application of stimulated Raman scattering (SRS) uses the benefit of a label-free molecular fingerprint to image the uptake and distribution of an alkyne-based drug in living cells. This method delivers information on cellular molecular composition and drug–cell interaction, showing the potential of SRS in drug development.Keywords
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